Agrocef 250Mg Injection

Introduction

How To Use

• This medication is normally given once or twice daily by injection into a vein or muscle as advised by your doctor. The dosage is determined by your  symptoms and treatment response. Unless your doctor tells you otherwise, it is advised to drink plenty of water while taking this medication.
• Take this antibiotic at regular intervals for the best results. Take this medicine at the same time(s) each day to help you remember.
• Even if your symptoms go away after a few days, keep taking this medicine for the full duration recommended  by your doctor. Stopping the drug too soon may cause the infection to recur. If your issue persists or worsens, inform your doctor.

Expert Advice

• This medication is to be administered by injection or infusion only.
• Contact prescriber if there is burning/swelling/redness/pain at injection or infusion or if there is rash, hives, itching, difficulty in breathing or swallowing, unrelieved diarrhea (watery stools), vaginal drainage or itching, mouth sores, blood, pus or mucus in stools or urine, easy bruising or bleeding, unusual chills or fever.
• Watery or bloody stools can occur 2 or more months after therapy and can be serious and require immediate treatment.
• Take sufficient amounts of fluids (2-3 liters per day) to maintain hydration, unless restricted by the prescriber.

Primary Uses

Indications

This medicine is indicated in severe respiratory, genitourinary (urinary and genital system), bone, joint, abdominal infections, sepsis (life threatening condition in response to infection) and meningitis (inflammation of meninges).

Side Effects

GI upset, skin reactions, blood dyscrasias (blood disorders) are some of its side effects. It may rarely cause pseudomembranous colitis (inflammation of large intestine due to overgrowth of clostridium difficile bacteria), raised liver enzymes, glucosuria (glucose in urine), oliguria (urine output less than 1mL/kg/h), hematuria (blood in urine), bronchospasm (spasm of airways), phlebitis (inflammation of vein) at injection site, urinary and biliary precipitates, nephrolithiasis (kidney stones), pancreatitis (inflammation of pancreas), haemolytic anemia (red cells are destroyed faster than they are made), positive coombs test (test used to detect antibodies against the surface of red blood cells) etc.

Contraindications

This medicine is contraindicated in patients with hypersensitivity to beta lactam drugs, in premature newborns having less than 41 weeks postmenstrual age; neonates over 41 weeks postmenstrual age with jaundice (a condition characterized by yellow discolouration of the skin, eyes and mucous membranes), hypoalbuminemia (low albumin levels) or acidosis (too much acid in body), concomitant treatment with IV calcium (including total parenteral nutrition containing calcium) in neonates over 41 weeks postmenstrual age – risk of precipitation in lungs and urine. It should not be used in hyperbilirubinemia (high bilirubin levels) neonates.

FAQS

What is ceftriaxone used for?

Cefriaxone is used to treat certain bacterial infections.

What is the contraindication of ceftriaxone?

It is contraindicated in hemolytic anemia (red cells are destroyed faster than they are made), diarrhea due to clostridium difficile bacteria, liver and gallbladder problems.

How long does ceftriaxone injection stays in our system?

The average elimination half-life in healthy adults is 5.8–8.7 hours. In patients with renal impairment, the average elimination half-life increases to 11.4–15.7 hours.

How do you give ceftriaxone injection?

1 gm ceftriaxone is dissolved in 10 ml of water. It is administered directly in vein over a period of 5 minutes.

What type of infections does ceftriaxone treat?

It is used to treat gonorrhea (sexually transmitted disease), pelvic inflammatory disease (infection of female reproductive organs), meningitis (inflammation of meninges outside the brain and spinal cord).